| I gama le-brand | I-ActiTide-AH3 |
| Inombolo ye-CAS. | 616204-22-9 |
| Igama le-INCI | I-Acetyl Hexapeptide-3 |
| Isakhiwo Samakhemikhali |  |
| Isicelo | I-lotion, i-serum, imaski, isihlanzi sobuso |
| Iphakheji | 1kg inetha ibhodlela ngalinye / 20kgs inetha isigubhu ngasinye |
| Ukubukeka | Uketshezi/Impushana |
| I-Acetyl hexapeptide-3(8) (Uketshezi) | 450-550ppm 900-1200ppm |
| Ukuhlanzeka (Powder) | 95% iminithi |
| Ukuncibilika | Amanzi ancibilikayo |
| Umsebenzi | Peptide series |
| Impilo yeshelufu | iminyaka engu-2 |
| Isitoreji | Gcina endaweni epholile neyomile, kude nokukhanya. 2~8℃okokugcina. |
| Umthamo | 2000-5000ppm |
Isicelo
I-anti wrinkle hexapeptide ActiTide-I-AH3 imele ukutholwa kwengoma enhle esekelwe endleleni yesayensi ukusuka ekwakhiweni okunengqondo kuye ekukhiqizweni kwe-GMP. Ucwaningo lwezinqubo eziyisisekelo zamakhemikhali ezinto eziphilayo zomsebenzi wokulwa nemibimbi kuye kwaholela kule hexapeptide eguquguqukayo ethathe umhlaba wezimonyo ngamandla.
Ekugcineni, ukwelashwa kwemibimbi okungaqhudelana nokusebenza kwe-Botulinum Toxin A kodwa kushiye eceleni ubungozi, imijovo kanye nezindleko eziphezulu: ActiTide-I-AH3.
Izinzuzo zezimonyo:
I-ActiTide-AH3 yehlisa ukujula kwemibimbi ebangelwa ukufinyela kwemisipha yokubonakala kobuso, ikakhulukazi ebunzini naseduze kwamehlo.
Isebenza kanjani i-ActiTide-AH3?
Imisipha iba yinkontileka lapho ithola i-neurotransmitter ehamba ngaphakathi kwe-vesicle. Inkimbinkimbi ye-SNARE (SNAp RE ceptor) ibalulekile kulokhu kukhululwa kwe-neurotransmitter ku-synapsis (A. Ferrer Montiel et al, The Journal of Biological Chemistry, 1997, 272, 2634-2638). Kuyi-ternary complex eyakhiwe amaprotheni i-VAMP, i-Syntaxin ne-SNAP-25. Le nkimbinkimbi ifana nehhuku yeselula ethwebula ama-vesicle futhi iwahlanganise nolwelwesi ukuze kukhishwe i-neurotransmitter.
I-ActiTide-AH3 ilingisa ukuphela kwe-N-terminal ye-SNAP-25 eqhudelana ne-SNAP-25 ngesikhundla senkimbinkimbi ye-SNARE, ngaleyo ndlela imodela ukwakheka kwayo. Uma inkimbinkimbi ye-SNARE ingasebenzi kahle, i-vesicle ayikwazi ukudokha futhi ikhulule ama-neurotransmitters ngendlela efanele futhi ngenxa yalokho ukufinyela kwemisipha kuyancishiswa, okuvimbela ukwakheka kwemigqa nemibimbi.
I-ActiTide-AH3 iyindlela ephephile, eshibhile, futhi ethambile kune-Botulinum Toxin, eqondise ngokwesihloko indlela efanayo yokubumba imibimbi ngendlela ehluke kakhulu.
