| I gama le-brand | I-ActiTide™ AH3(Liquefied 1000) |
| Inombolo ye-CAS. | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| Igama le-INCI | I-Acetyl Hexapeptide-8; I-Glycerin; Butylene Glycol; Amanzi; I-Hydroxyacetophenone; 1,2-Hexanediol |
| Isicelo | I-Lotion, iSerum, Imaski, Isihlanzi sobuso |
| Iphakheji | 1kg/ibhodlela |
| Ukubukeka | Sula uketshezi olusobala olunephunga eliyisici |
| Ukuncibilika | Amanzi ancibilikayo |
| Umsebenzi | Peptide series |
| Impilo yeshelufu | iminyaka engu-2 |
| Isitoreji | Gcina isitsha sivalwe ngokuqinile endaweni epholile, eyomile eku-2 - 8°C. |
| Umthamo | 3.0-10.0% |
Isicelo
Ucwaningo lwezindlela eziyisisekelo zokunqanda imibimbi luholele ekutholweni kwe-ActiTide™ AH3, i-hexapeptide esungulwe ngendlela yesayensi ukusuka kumklamo ophusile kuya ekukhiqizweni kwe-GMP, kube nemiphumela emihle.
I-ActiTide™ AH3 iletha ukusebenza ngempumelelo kokunciphisa imibimbi okuqhathaniswa nohlobo A lwe-Botulinum Toxin, kuyilapho igwema izingozi zokujova futhi inikeza ukusebenza ngempumelelo kwezindleko.
Izinzuzo Zezimonyo:
I-ActiTide™ AH3 yehlisa ukujula kokushwabana okubangelwa ukufinyela kwemisipha yobuso, ibe nemiphumela ezwakalayo ebunzini kanye nemibimbi ye-periocular.
Indlela Yesenzo:
Ukufinyela kwemisipha kwenzeka lapho kukhululwa i-neurotransmitter kuma-synaptic vesicles. I-SNARE complex - i-ternary assembly yamaprotheni e-VAMP, i-Syntaxin, ne-SNAP-25 - ibalulekile ku-vesicle docking kanye ne-neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Le nkimbinkimbi isebenza njengehhuku yeselula, ibamba ama-vesicles futhi iqhube ukuhlanganiswa kwe-membrane.
Njenge-mimetic yesakhiwo ye-SNAP-25 N-terminus, i-ActiTide™ AH3 incintisana ne-SNAP-25 ukuze ifakwe kunxanxathela ye-SNARE, imodela ukuhlanganiswa kwayo. Ukungaqini kahle kwenkimbinkimbi ye-SNARE kukhubaza ukudotshwa kwe-vesicle kanye nokukhululwa kwe-neurotransmitter okulandelayo, okuholela ekunciphiseni ukufinyela kwemisipha kanye nokuvimbela ukushwabana nokwakheka komugqa omuhle.
I-ActiTide™ AH3 iyindlela ephephile, eyonga kakhulu, futhi emnene kune-Botulinum Toxin Type A. Iqondise ngokuqondile indlela efanayo yokushwabana kodwa isebenza ngendlela ehlukile.
