| I gama le-brand | I-ActiTide™ AH3 (Encibilikisiwe 1000) |
| Inombolo ye-CAS | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| Igama le-INCI | I-Acetyl Hexapeptide-8; I-Glycerin; I-Butylene Glycol; Amanzi; I-Hydroxyacetophenone; I-1,2-Hexanediol |
| Isicelo | Iloshini, Ama-Serum, Imaski, Isihlanzi Sobuso |
| Iphakheji | 1kg/ibhodlela |
| Ukubukeka | Uketshezi olucacile olucacile olunephunga elihlukile |
| Ukuncibilika | Amanzi ancibilikayo |
| Umsebenzi | Uchungechunge lwe-Peptide |
| Isikhathi sokuphelelwa yisikhathi | iminyaka engu-2 |
| Isitoreji | Gcina isitsha sivalwe kahle endaweni epholile, eyomile ku-2 - 8°C. |
| Isilinganiso | 3.0-10.0% |
Isicelo
Ucwaningo ngezindlela eziyisisekelo zokulwa nemibimbi luholele ekutholakaleni kwe-ActiTide™ AH3, i-hexapeptide entsha eyathuthukiswa ngendlela yesayensi kusukela ekwakhiweni okunengqondo kuya ekukhiqizweni kwe-GMP, kwaba nemiphumela emihle.
I-ActiTide™ AH3 inikeza ukusebenza kahle kokunciphisa imibimbi okufana nohlobo lwe-Botulinum Toxin A, ngenkathi igwema izingozi zomjovo futhi inikeza ukusebenza kahle okukhulu kwezindleko.
Izinzuzo Zobuhle:
I-ActiTide™ AH3 yehlisa ukujula kwemibimbi okubangelwa ukufinyela kwemisipha yobuso, okunemiphumela evelele ebunzini kanye nemibimbi ye-periocular.
Indlela Yokusebenza:
Ukufinyela kwemisipha kwenzeka lapho kukhululwa i-neurotransmitter kuma-vesicle e-synaptic. I-SNARE complex – i-ternary assembly yama-protein e-VAMP, i-Syntaxin, ne-SNAP-25 – ibalulekile ekubekweni kwe-vesicle kanye ne-neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272:2634-2638). Le complex isebenza njenge-hook yeselula, ibamba ama-vesicle futhi iqhube ukuhlangana kwe-membrane.
Njengokulingisa kwesakhiwo se-SNAP-25 N-terminus, i-ActiTide™ AH3 incintisana ne-SNAP-25 ukuze ifakwe ku-SNARE complex, iguqula ukuhlanganiswa kwayo. Ukuwohloka kwe-SNARE complex kuphazamisa ukugoba kwe-vesicle kanye nokukhululwa kwe-neurotransmitter okulandelayo, okuholela ekunciphiseni ukufinyela kwemisipha kanye nokuvimbela ukwakheka kwemibimbi kanye nomugqa omncane.
I-ActiTide™ AH3 iyindlela ephephile, engabizi kakhulu, futhi ethambile esikhundleni se-Botulinum Toxin Type A. Ihlose ngqo indlela efanayo yokwakheka kwemibimbi kodwa isebenza ngendlela ehlukile.
