| I gama le-brand | I-ActiTide-AH3(Liquefied 500) |
| Inombolo ye-CAS. | 7732-18-5; 616204-22-9; 1117-86-8 |
| Igama le-INCI | Amanzi; I-Acetyl hexapeptide-8; I-Caprilyl glycol |
| Isicelo | I-lotion, iSerum, Imaski, isihlanzi sobuso |
| Iphakheji | 1kg/ibhodlela |
| Ukubukeka | Uketshezi olucacile nolusobala |
| Okuqukethwe kwe-Peptide | 0.045 – 0.060% |
| Ukuncibilika | Amanzi ancibilikayo |
| Umsebenzi | Peptide series |
| Impilo yeshelufu | iminyaka engu-2 |
| Isitoreji | Gcina endaweni epholile neyomile, kude nokukhanya. 2~8°C ukuze ulondoloze |
| Umthamo | 3.0-10.0% |
Isicelo
Ucwaningo lwezindlela eziyisisekelo zokunqanda imibimbi luholele ekutholweni kwe-ActiTide-AH3, i-hexapeptide esungulwe ngendlela yesayensi ukusuka kumklamo ophusile kuya ekukhiqizweni kwe-GMP, kube nemiphumela emihle.
I-ActiTide-AH3 iletha ukusebenza ngempumelelo kokunciphisa imibimbi okuqhathaniswa nohlobo A lwe-Botulinum Toxin, kuyilapho igwema izingozi zokujova futhi inikeza ukusebenza kahle kwezindleko.
Izinzuzo Zezimonyo:
I-ActiTide-AH3 yehlisa ukujula kokushwabana okubangelwa ukufinyela kwemisipha yobuso, ibe nemiphumela evelele ebunzini kanye nemibimbi ye-periocular.
Indlela Yesenzo:
Ukufinyela kwemisipha kwenzeka lapho i-neurotransmitter ikhishwa kuma-synaptic vesicles. I-SNARE complex - i-ternary assembly yamaprotheni e-VAMP, i-Syntaxin, ne-SNAP-25 - ibalulekile ku-vesicle docking kanye ne-neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Le nkimbinkimbi isebenza njengehuku lamaselula, ibamba ama-vesicles futhi iqhube ukuhlanganiswa kwe-membrane.
Njenge-mimetic yesakhiwo ye-SNAP-25 N-terminus, i-ActiTide-AH3 incintisana ne-SNAP-25 ukuze ifakwe kunxanxathela ye-SNARE, imodela ukuhlanganiswa kwayo. Ukungaqini kahle kwenkimbinkimbi ye-SNARE kukhubaza ukudotshwa kwe-vesicle kanye nokukhululwa kwe-neurotransmitter okulandelayo, okuholela ekunciphiseni ukufinyela kwemisipha kanye nokuvimbela ukushwabana nokwakheka komugqa omuhle.
I-ActiTide-AH3 iyindlela ephephile, eyonga kakhulu, futhi emnene kune-Botulinum Toxin Type A. Iqondise ngokuqondile indlela efanayo yokwenza imibimbi kodwa isebenza ngendlela ehlukile.
