| I gama le-brand: | I-PromaCare LD1-PDRN |
| Inombolo ye-CAS: | 7732-18-5; 90046-12-1; /; 70445-33-9; 5343-92-0 |
| Igama le-INCI: | Amanzi; I-Laminaria Digitata Extract; I-Sodium DNA; I-Ethylhexylglycerin; I-Pentylene Glycol |
| Isicelo: | Umkhiqizo wochungechunge olududuzayo; Umkhiqizo wochungechunge olulwa nokuvuvukala; Umkhiqizo wochungechunge olulwa nokuguga |
| Iphakheji: | 30ml/ibhodlela, 500ml/ibhodlela noma ngokwezidingo zamakhasimende |
| Ukubukeka: | Uketshezi oluphuzi olukhanyayo kuya konsundu |
| Ukuncibilika: | Incibilika emanzini |
| i-pH (1% isixazululo samanzi): | 4.0 – 9.0 |
| Okuqukethwe kwe-DNA ppm: | imizuzu eyi-1000 |
| Isikhathi sokuphelelwa yisikhathi: | iminyaka engu-2 |
| Isitoreji: | Kufanele igcinwe ku-2~8°C esitsheni esivalwe kahle nesingenakukhanya. |
| Isilinganiso: | 0.01 – 2% |
Isicelo
I-PromaCare LD1-PDRN iyisithako sama-polysaccharide angaphakathi kwamangqamuzana kanye nezingcezu ze-DNA ezivela ku-palmate kelp. Abadobi basogwini bokuqala bathola ukuthi i-kelp echotshoziwe inekhono elikhethekile lokukhuthaza ukugcinwa komswakama wesikhumba kanye nokulwa nokuvuvukala. Ngo-1985, kwasungulwa futhi kwafakwa umuthi wokuqala wasolwandle i-sodium alginate. Inemisebenzi yokulwa nokuvuvukala, yokulwa nokuvuvukala, yokulwa namagciwane, ukuthambisa kanye neminye, okwenza ibe nekusasa eliqhakazile emkhakheni wocwaningo lwezokwelapha. Njengezinto zokusetshenziswa kwezimonyo nezokwelapha, i-PDRN isetshenziswa kabanzi ebuhleni bezokwelapha, imikhiqizo yamakhemikhali yansuku zonke, ukudla okunempilo kanye neminye imikhakha. I-PromaCare LD1-PDRN iyinhlanganisela ye-fucoidan ne-deoxyribonucleic acid ekhishwe kuI-Laminaria japonicangenqubo yokuhlanza eqinile futhi inokuphepha okuphezulu kanye nokuqina.
I-PromaCare LD1-PDRN ibopha i-adenosine A2A receptor ukuze iqalise izindlela eziningi zokubonisa izimpawu ezandisa izici zokulwa nokuvuvukala, zinciphise izici zokuvuvukala, futhi zivimbele izimpendulo zokuvuvukala. Ikhuthaza ukwanda kwe-fibroblast, i-EGF, i-FGF, ukukhiqizwa kwe-IGF, ishintshe isimo sangaphakathi sesikhumba esonakele. Ikhuthaza i-VEGF ukukhiqiza ama-capillary, inikeze izakhamzimba zokulungisa isikhumba nokukhipha izinto zokuguga. Ngokuhlinzeka nge-purine noma i-pyrimidine njengendlela yokulungisa, isheshisa ukwakheka kwe-DNA futhi ivumela isikhumba ukuthi siphinde sikhule ngokushesha.
1. Ukuqina okuhlanganisiwe
Ama-oligosaccharide e-alginate angavimbela ngokuphelele (100%) ukuwohloka kwamafutha kuma-emulsions, okungcono ngo-89% kune-ascorbic acid.
2. Izakhiwo zokulwa nokuvuvukala
I-oligosaccharide ensundu ingabopha kuma-selectin, ngaleyo ndlela ivimbele ukufuduka kwamangqamuzana amhlophe egazi endaweni ethelelekile, ngaleyo ndlela ivimbele ukuthuthukiswa kokuvuvukala futhi inciphise kakhulu ukucasuka.
3. Vimbela i-apoptosis yamaseli, i-anti-oxidation
I-oligosaccharide ensundu ye-alginate ingakhuthaza ukuvezwa kwe-Bcl-2 gene, ivimbele ukuvezwa kwe-Bax gene, ivimbele ukusebenza kwe-caspase-3 okubangelwa yi-hydrogen peroxide, futhi ivimbele ukuqhekeka kwe-PARP, okubonisa umphumela wayo wokuvimbela ku-apoptosis yamaseli.
4. Ukugcinwa kwamanzi
I-oligosaccharide ensundu inezici ze-polymer ye-macromolecular, engakwanelisa kokubili izakhiwo zokwakha ifilimu kanye nezokusekela. Ngenxa yokusatshalaliswa kwayo okufanayo kwe-macromolecular, kuphinde kwafakazelwa ukuthi inezakhiwo ezinhle zokugcina amanzi kanye nokwakha ifilimu.
