Igama lokuhweba | I-UniAPI-PBS |
I-CAS | 1405-20-5 |
Igama Lomkhiqizo | I-Polymyxin B sulfate |
Ukubukeka | Impushana emhlophe noma ecishe ibe mhlophe |
Ukuncibilika | Amanzi ancibilikayo |
Isicelo | Umuthi |
Isivivinyo | Isamba se-polymyxin B1, B2, B3 kanye ne-B1-I: 80.0% minPolymyxin B3: 6.0% maxPolymyxin B1-I: 15.0% max |
Iphakheji | 1kg inethi ngekani le-aluminium |
Impilo yeshelufu | iminyaka engu-2 |
Isitoreji | Gcina endaweni epholile neyomile, kude nokukhanya. 2~8℃ yokugcina. |
Isakhiwo Samakhemikhali |
Isicelo
I-Polyxin B sulfate iyimithi elwa namagciwane ene-cationic surfactant, ingxube ye-polyxin B1 ne-B2, engathuthukisa ukungeneka kwe-membrane yeseli. Cishe ayinaphunga. Kuyazwela ekukhanyeni. I-Hygroscopic. Incibilika emanzini, inyibilika kancane ku-ethanol.
Umphumela womtholampilo
I-spectrum ye-antibacterial kanye nokusebenza komtholampilo kufana ne-polymyxin e. inemiphumela evimbelayo noma ye-bactericidal kumagciwane angenayo i-Gram-negative, njenge-Escherichia coli, i-Pseudomonas aeruginosa, i-paraescherichia coli, i-Klebsiella pneumoniae, i-acidophilus, i-pertussis kanye ne-dysentery. Ngokomtholampilo, isetshenziselwa ikakhulukazi ukutheleleka okubangelwa amagciwane azwelayo, ukutheleleka kwesistimu yomchamo okubangelwa i-Pseudomonas aeruginosa, iso, uqhoqhoqho, i-meningitis, i-sepsis, ukutheleleka kokusha, ukutheleleka kwesikhumba nolwelwesi lwamafinyila, njll.
isenzo semithi
Inomphumela we-antibacterial ku-Pseudomonas aeruginosa, i-Escherichia coli, i-Klebsiella pneumoniae, i-Haemophilus, i-enterobacter, i-Salmonella, i-Shigella, i-pertussis, i-pasteurella ne-Vibrio. I-Proteus, i-Neisseria, i-Serratia, i-pruvidens, i-Gram-positive bacteria kanye ne-obligate anaerobes ayengazweli kule mithi. Kwakukhona ukumelana phakathi kwalo muthi ne-polymyxin E, kodwa kwakungekho ukumelana phakathi kwalo muthi namanye ama-antibiotic.
Isetshenziselwa ikakhulukazi isilonda, i-urinary tract, iso, indlebe, isifo soqhoqhoqho esibangelwa i-Pseudomonas aeruginosa nezinye i-Pseudomonas. Ingasetshenziselwa futhi i-sepsis ne-peritonitis.